包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Canonical SMILES | O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCCCCC/C=C\CCCCCCCC)=O)=O)=O)(O)=O)(O)=O)[C@H]1OP(O)(O)=O.[Na] |
分子式 | C39H68N7O17P3S • Na |
分子量 | 1055 |
溶解度 | Water: 10mg/mL |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Oleoyl-coenzyme A (oleoyl-CoA) is a thioester of oleic acid and CoA . It is a substrate for several acyl-CoA-dependent enzymes, including acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1), ACAT-2, acyl-CoA dehydrogenase-9 (ACAD-9), membrane-bound O-acyltransferase 1 (MBOAT1), and MBOAT2.1,2,3Oleoyl-CoA binds the fatty acid metabolism regulator protein (FadR) promoter inE. coli(Ki= 0.005 µM).4Oleoyl-CoA (1 µM) activates sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 inXenopusoocytes.5 1.Seo, T., Oelkers, P.M., Giattina, M.R., et al.Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cellsBiochemistry40(15)4756-4762(2001) 2.Ensenauer, R., He, M., Willard, J.-M., et al.Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial β-oxidation of unsaturated fatty acidsJ. Biol. Chem.280(37)32309-32316(2005) 3.GijÓn, M.A., Riekhof, W.R., Zarini, S., et al.Lysophospholipid acyltransferases and arachidonate recycling in human neutrophilsJ. Biol. Chem.283(44)30235-30245(2008) 4.DiRusso, C.C., Heimert, T.L., and Metzger, A.K.Characterization of FadR, a global transcriptional regulator of fatty acid metabolism in Escherichia coli. Interaction with the fadB promoter is prevented by long chain fatty acyl coenzyme AJ. Biol. Chem.267(12)8685-8691(1992) 5.Gribble, F.M., Proks, P., Corkey, B.E., et al.Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoAJ. Biol. Chem.273(41)26383-26387(1998) |