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PKA Inhibitor(5-24)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:99534-03-9
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
PKA Inhibitor (5-24) 是一种有效的、竞争性的、合成的 PKA(cAMP 依赖性蛋白激酶)肽抑制剂,Ki 为 2.3 nM。
Cas No.99534-03-9
Canonical SMILESO=C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC1=CN=CN1)[C@@]([C@H](CC)C)([H])NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC([C@@]([C@@H](C)O)([H])NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CO)NC([C@@H](NC([C@@]([C@H](CC)C)([H])NC([C@@H](NC
分子式C94H148N32O31
分子量2222.4
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235 and Phe239 form a sandwich-like structure with residue Phe10 of PKI (5-24).