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PRT 4165
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PRT 4165图片
CAS NO:31083-55-3
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品名称
PRT4165, PRT-4165
产品介绍

生物活性

PRT 4165是Bmi1/Ring1A抑制剂,Bmi1/Ring1A是多梳抑制复合物1(PRC1)的亚基。它可以防止Bmi1/Ring1A介导的泛素化和拓扑异构酶2alpha的药物诱导降解。

化学数据

目录号A15453
作用机制Inhibitor (抑制剂)
M. Wt235.24
FormulaC15H9NO2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.31083-55-3
SynonymsPRT4165, PRT-4165
SMILESO=C(C1=CC=CC=C1C/2=O)C2=C\C3=CC=CN=C3

溶解度

In vitroDMSO10 mg/mL (42.51 mM)
WaterInsoluble
Ethanol3 mg/mL (12.75 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM42.51 mL212.55 mL425.1 mL
0.5 mM8.5 mL42.51 mL85.02 mL
1 mM4.25 mL21.25 mL42.51 mL
5 mM0.85 mL4.25 mL8.5 mL

*The above data is based on the productmolecular weight 235.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.