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Epitinib succinate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Epitinib succinate图片
CAS NO:2252334-12-4
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Epitinib succinate 是一种具有口服活性和选择性的表皮生长因子受体酪氨酸激酶抑制剂 (EGFR-TKI)，可以透过血脑屏障。Epitinib succinate 可用于癌症研究。
Cas No.2252334-12-4
别名HMPL-813 succinate
分子式C28H32N6O6
分子量548.59
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer[1][2].

Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration[1][2].

[1]. Zhou et al. The safety profile of a selective EGFR TKI epitinib (HMPL-813) in patients with advanced solid tumors and preliminary clinical efficacy in EGFRm+ NSCLC patients with brain metastasis. Journal of Clinical Oncology 2016 34:15_suppl, e20502-e20502
[2]. Zhou et al. Phase I study of the safety and pharmacokinetics of epitinib, an oral EGFR tyrosine kinase inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology 2013 31:15_suppl, e19042-e19042