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Pseudouridine 5'-triphosphate trisodium
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Pseudouridine 5'-triphosphate trisodium图片
包装:5.5mg(100 mM * 100 uL in Water)
市场价:4320元

产品介绍
Pseudouridine 5'-triphosphate (Pseudo-UTP) 是聚合酶介导的 RNA 合成中最常用的修饰核苷酸之一。与含有 UTP 的未修饰的 mRNA 相比，含Pseudo-UTP的 mRNA的显示出更好的核酸酶稳定性，免疫原性和翻译特性。
别名Pseudo-UTP trisodium
分子式C9H12N2Na3O15P3
分子量550.09
储存条件Solution, -20°C, 2 years
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pseudouridine-5'-triphosphate (Pseudo-UTP) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties[1].
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[1]. Muthian Shanmugasundaram, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):356-62.