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NSC 107512
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NSC 107512图片
CAS NO:22242-89-3
包装:25mg
市场价:11250元

产品介绍
NSC 107512 是一种有效的细胞周期蛋白依赖性激酶 9 (CDK9) 抑制剂。NSC 107512 是一类桑吉霉素样分子 (SLM)。NSC 107512 抑制多发性骨髓瘤肿瘤的生长并诱导细胞凋亡 (apoptosis)。
Cas No.22242-89-3
分子式C12H16N6O5
分子量324.29
溶解度DMSO : 170 mg/mL (524.22 mM; Need ultrasonic)
储存条件Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors[1].

[1]. Dolloff NG, et al. Sangivamycin-like molecule 6 exhibits potent anti-multiple myeloma activity through inhibition of cyclin-dependent kinase-9. Mol Cancer Ther. 2012;11(11):2321-2330.