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Uridine-d2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Uridine-d2图片
CAS NO:40632-21-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Uridine-d2 是氘标记的 Uridine。
Cas No.40632-21-1
别名尿苷-5,6-D2,β-Uridine-d2
Canonical SMILESO[C@H]1[C@@](N2C(NC(C([2H])=C2[2H])=O)=O)([H])O[C@@H]([C@H]1O)CO
分子式C9H10D2N2O6
分子量246.2
溶解度DMF: 16 mg/ml,DMSO: 10 mg/ml,PBS (pH 7.2): 5 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Uridine-d2is intended for use as an internal standard for the quantification of uridine by GC- or LC-MS. Uridine is a pyrimidine nucleoside composed of uracil and ribose.1It forms complementary base pairs with adenosine in RNA.2Uridine can be catabolized to uracilviauridine phosphorylase, and it can be phosphorylated to uridine-5’-monophosphate by uridine-cytidine kinase (UCK).1,3It is replaced with thymidine in DNA.4

1.Yamamoto, T., Koyama, H., Kurajoh, M., et al.Biochemistry of uridine in plasmaClin. Chim. Acta412(19-20)1712-1724(2011) 2.Zinshteyn, B., and Nishikura, K.Adenosine-to-inosine RNA editingWiley Interdiscip. Rev. Syst. Biol. Med.1(2)202-209(2009) 3.Van Rompay, A.R., Norda, A., LindÉn, K., et al.Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinasesMol. Pharmacol.59(5)1181-1186(2001) 4.Knoop, V.When you can’t trust the DNA: RNA editing changes transcript sequencesCell. Mol. Life Sci.68(4)567-586(2011)