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IU1-248
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IU1-248图片
CAS NO:2307472-03-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
IU1-248 是 IU1 的衍生物,是一种有效的、选择性的 USP14 抑制剂,其 IC50 为 0.83 μM。
Cas No.2307472-03-1
分子式C20H23N3O2
分子量337.42
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.

IU1-248 exhibits an IC50 value of 0.83 μM toward USP14, which is comparable to that of IU1-47 (IC50=0.68 μM) and 10-fold more potent than that of IU1 (IC50=12.25 μM)[1].

[1]. Yiwei Wang, et al. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res. 2018 Dec;28(12):1186-1194.