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L-Proline-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Proline-d3图片
CAS NO:65807-22-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
An internal standard for the quantification of L-proline
Cas No.65807-22-9
别名L-脯氨酸 d3
Canonical SMILESOC([C@@]1([2H])NC([2H])([2H])CC1)=O
分子式C5H6D3NO2
分子量118.2
溶解度Methanol: slightly soluble,Water: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

L-Proline-d3is intended for use as an internal standard for the quantification of L-proline by GC- or LC-MS. L-Proline is a nonessential amino acid.1It contains a pyrrolidine ring, which contains the α-amino nitrogen, and is highly rigid, properties that affect protein conformation and folding and can cause kinks and turns in protein secondary structure.1,2It is a substrate for the proton-coupled amino acid transporter 1 (PAT1) and an inhibitor of acetylcholinesterase (AChE; Ki= 86 µM).3,4L-Proline accumulates in plants under environmental stress and is important for environmental stress tolerance through its involvement in protein synthesis, redox balance maintenance, osmoprotection, and signaling.5

1.Lodish, H., Berk, A., Zipursky, L., et al.Hierarchical structure of proteinsMolecular cell biology(2000) 2.MacArthur, M.W., and Thornton, J.M.Influence of proline residues on protein conformationJ. Mol. Biol.218(2)397-412(1991) 3.Thondorf, I., Voigt, V., SchÄfer, S., et al.Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1)Bioorg. Med. Chem.19(21)6409-6418(2011) 4.VÉgner, L., Peragovics, Á., Tombor, L., et al.Experimental confirmation of new drug-target interactions predicted by drug profile matchingJ. Med. Chem.56(21)8377-8388(2013) 5.Szabados, L., and SavourÉ, A.Proline: A multifunctional amino acidTrends Plant Sci.15(2)89-97(2010)