CAS NO: | 65807-22-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
Cas No. | 65807-22-9 |
别名 | L-脯氨酸 d3 |
Canonical SMILES | OC([C@@]1([2H])NC([2H])([2H])CC1)=O |
分子式 | C5H6D3NO2 |
分子量 | 118.2 |
溶解度 | Methanol: slightly soluble,Water: slightly soluble |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | L-Proline-d3is intended for use as an internal standard for the quantification of L-proline by GC- or LC-MS. L-Proline is a nonessential amino acid.1It contains a pyrrolidine ring, which contains the α-amino nitrogen, and is highly rigid, properties that affect protein conformation and folding and can cause kinks and turns in protein secondary structure.1,2It is a substrate for the proton-coupled amino acid transporter 1 (PAT1) and an inhibitor of acetylcholinesterase (AChE; Ki= 86 µM).3,4L-Proline accumulates in plants under environmental stress and is important for environmental stress tolerance through its involvement in protein synthesis, redox balance maintenance, osmoprotection, and signaling.5 1.Lodish, H., Berk, A., Zipursky, L., et al.Hierarchical structure of proteinsMolecular cell biology(2000) 2.MacArthur, M.W., and Thornton, J.M.Influence of proline residues on protein conformationJ. Mol. Biol.218(2)397-412(1991) 3.Thondorf, I., Voigt, V., SchÄfer, S., et al.Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1)Bioorg. Med. Chem.19(21)6409-6418(2011) 4.VÉgner, L., Peragovics, Á., Tombor, L., et al.Experimental confirmation of new drug-target interactions predicted by drug profile matchingJ. Med. Chem.56(21)8377-8388(2013) 5.Szabados, L., and SavourÉ, A.Proline: A multifunctional amino acidTrends Plant Sci.15(2)89-97(2010) |