CAS NO: | 1637542-32-5 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 1637542-32-5 |
Canonical SMILES | ClC1=C([C@@H](O)C2=NN=C(OC)C=C2)C=C(C3=C4C=CC(N5CCOCC5)=CC4=NC=N3)C(F)=C1 |
分子式 | C24H21ClFN5O3 |
分子量 | 481.91 |
溶解度 | DMSO : 100 mg/mL (207.51 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | (R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1]. DNA-PK|7-30 nM (IC50) Rac-Nedisertib (Compound 135) less actively inhibits DNA-PK, with an IC50 in the range of 7-30 nM[1]. [1]. Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1. |