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Phomopsinamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phomopsinamine图片
CAS NO:89085-54-1
包装与价格:
包装价格(元)
100µg电议
500µg电议

产品介绍
An inhibitor of microtubule polymerization
Cas No.89085-54-1
Canonical SMILESClC1=CC([C@H](O)[C@@H]2NC)=CC(O[C@@](CC)(C)[C@@](NC([C@H](C(C)=C)NC2=O)=O)([H])C(N3[C@@](C(N/C(C(N)=O)=C(CC)\C)=O)([H])C=CC3)=O)=C1O
分子式C32H43ClN6O8
分子量675.2
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Phomopsinamine is an inhibitor of microtubule polymerization and a derivative of phomopsin A .1It inhibits the rate and extent of polymerization of tubulin isolated from ovine brain (IC50s = 0.53 and 0.59 µM, respectively).

1.Lacey, E., Edgar, J.A., and Culvenor, C.C.Interaction of phomopsin A and related compounds with purified sheep brain tubulinBiochem. Pharmacol.36(13)2133-2138(1987)