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CMD178
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
CMD178是一种重要的多肽,能够持续地通过抑制IL-2/sIL-2Rα信号通路来减少Foxp3和STAT5的表达。CMD178是STAT5的抑制剂,并可抑制Treg细胞的发育。
分子式C46H59N9O7
分子量850.03
溶解度Soluble in Water
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling. CMD178 also is an inhibitor of STAT5 and inhibit Treg cell development[1].

[1]. Price-Troska T, et al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2018 Apr 26.