IOX4 是一种选择性 HIF 脯氨酰羟化酶 2 (PHD2) 抑制剂，IC50 值为 1.6 nM，在细胞和野生型小鼠中诱导 HIFα，并在脑组织中显着诱导。
| Cas No. | 1154097-71-8 |
| 化学名 | 1,1-dimethylethyl ester 6-[2,5-dihydro-5-oxo-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-1-yl]-3-pyridinecarboxylic acid |
| Canonical SMILES | CC(C)(C)OC(C1=CN=C(N2NC=C(N3C=CN=N3)C2=O)C=C1)=O |
| 分子式 | C15H16N6O3 |
| 分子量 | 328.3 |
| 溶解度 | ≤1mg/ml in ethanol;20mg/ml in DMSO;25mg/ml in dimethyl formamide |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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