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2-Chloroadenine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-Chloroadenine图片
CAS NO:1839-18-5
包装与价格：
包装价格(元)
250mg电议
500mg电议
1 g电议

产品介绍
A heterocyclic building block
Cas No.1839-18-5
别名2-氯-6-氨基嘌呤
Canonical SMILESNC1=C2C(N=CN2)=NC(Cl)=N1
分子式C5H4ClN5
分子量169.6
溶解度Ethanol: slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Chloroadenine is a heterocyclic building block that has been used in the synthesis of adenosine antimetabolites with antineoplastic activity.1It is also the major catabolite of 2-chloro-2'-deoxyadenosine.2

1.Bauta, W.E., Schulmeier, B.E., Burke, B.J., et al.A new process for antineoplastic agent clofarabineOrg. Proc. Res. Dev.8(6)889-896(2004) 2.Bontemps, F., Delacauw, A., Cardoen, S., et al.Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-29-deoxyadenosineBiochem. Pharmacol.59(10)1237-1243(2000)