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FG-2216
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FG-2216图片
CAS NO:223387-75-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
YM-311
产品介绍

生物活性

FG-2216是一种有效的HIF-脯氨酰羟化酶抑制剂,对PDH2酶的IC50为3.9 uM;生物利用度并在体内诱导显着且可逆的Epo诱导。

靶点信息

PHD2
3.9 μM

化学数据

目录号A15530
作用机制Inhibitor (抑制剂)
M. Wt280.66
FormulaC12H9ClN2O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.223387-75-5
SynonymsYM-311
SMILESC1=CC=C2C(=C1)C(=C(N=C2Cl)C(=O)NCC(=O)O)O

溶解度

In vitro (25°C)DMSO48 mg/mL (171.02 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+40% PEG 300+2% Twenn 80+ddH2O28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM35.63 mL178.15 mL356.3 mL
0.5 mM7.13 mL35.63 mL71.26 mL
1 mM3.56 mL17.82 mL35.63 mL
5 mM0.71 mL3.56 mL7.13 mL

*The above data is based on the productmolecular weight 280.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.