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Honokiol DCA
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Honokiol DCA图片
CAS NO:1620160-42-0
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Honokiol DCA (Honokiol dichloroacetate) 是 Honokiol 的二氯乙酸酯类似物。Honokiol DCA 在体外可以抑制人前列腺癌细胞的生长并抑制雄激素受体 (AR) 蛋白水平。
Cas No.1620160-42-0
别名Honokiol dichloroacetate
分子式C22H18Cl4O4
分子量488.19
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1].

Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner[1].Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells[1].Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells[1].Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells[1].

Honokiol类似物

[1]. Hahm ER, et, al. Honokiol inhibits androgen receptor activity in prostate cancer cells. Prostate. 2014 Apr;74(4):408-20.