| 包装 | 价格(元) |
| 500 μg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Canonical SMILES | OC1=CC(CC[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])[C@@H](O)[C@@H](O)[C@@H]4O)=C3C=C1.O |
| 分子式 | C18H24O4.XH2O |
| 分子量 | 304.4 |
| 溶解度 | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol and estriol during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ERα over ERβ and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium).1,2In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.1,2 1.Coelingh Bennink, H.J.T., Holinka, C.F., and Diczfalusy, E.Estetrol review: Profile and potential clinical applicationsClimacteric.11(Suppl 1)47-58(2008) 2.Giretti, M.S., Guevara, M.M.M., Cecchi, E., et al.Effects of Estetrol on Migration and Invasion in T47-D Breast Cancer Cells through the Actin CytoskeletonFront.Endocrinol.(Lausanne)5(80)1-8(2014) |
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