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BLZ945
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BLZ945图片
CAS NO:953769-46-5
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品名称
BLZ 945, BLZ-945
产品介绍

生物活性

BLZ945是有效的选择性CSF-1R激酶抑制剂。它减弱了TAM的周转率,同时增加了浸润宫颈癌和乳腺癌的CD8+ T细胞的数量。

靶点信息

CSF-1R
1 nM

化学数据

目录号A15540
作用机制Inhibitor (抑制剂)
M. Wt398.4
FormulaC20H22N4O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.953769-46-5
SynonymsBLZ 945, BLZ-945
SMILESCNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O

溶解度

In vitro (25°C)DMSO77 mg/mL (193.23 mM)
WaterInsoluble
EthanolWarmed: 3 mg/mL
In vivo4% DMSO+30% PEG 300+ddH2O2.3 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.1 mL125.5 mL251 mL
0.5 mM5.02 mL25.1 mL50.2 mL
1 mM2.51 mL12.55 mL25.1 mL
5 mM0.5 mL2.51 mL5.02 mL

*The above data is based on the productmolecular weight 398.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.