| CAS NO: | 736945-96-3 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 736945-96-3 |
| Canonical SMILES | O=C(C1=CSC(NC2=CC=C(OC)C=C2)=N1)N(C3)CCC4=C3C=CC=C4 |
| 分子式 | C20H19N3O2S |
| 分子量 | 365.5 |
| 溶解度 | DMSO: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GSK 417651A is an inhibitor of transient receptor potential canonical 3 (TRPC3) and TRPC6 (IC50=~0.4 µM for both).1It inhibits migration of isolated human fibroblastic valve interstitial cells into the wounded area in a scratch test assay when used at a concentration of 2 µM.2 1.Xu, X., Lozinskaya, I., Costell, M., et al.Characterization of small molecule TRPC3 and TRPC6 agonist and antagonistsBiophys. J.104(2)454A(2013) 2.Al-Shammari, H., Latif, N., Sarathchandra, P., et al.Expression and function of mechanosensitive ion channels in human valve interstitial cellsPLoS One15(10)e0240532(2020) |
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