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m-PEG5-2-methylacrylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
m-PEG5-2-methylacrylate图片
CAS NO:48074-75-5
包装与价格:
包装价格(元)
250mg电议
500mg电议
1g电议

产品介绍
m-PEG5-2-methylacrylate 是一种 PROTAC linker,属于 PEG 和 Alkyl/ester 类,可用于合成 PROTAC。
Cas No.48074-75-5
分子式C15H28O7
分子量320.38
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-basedPROTAC linkercan be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Yong Ku Kwon,et al. Reduced excimer formation in polyfluorenes by introducing coil-like poly[penta(ethylene glycol) methyl ether methacrylate] block segments. Macromolecules, 2009, 42(3), 887-891.