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(-)-pareruptorin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(-)-pareruptorin A图片
CAS NO:73069-25-7
包装:20mg
市场价:1775元

产品介绍
(-)-pareruptorin A 是 cis-khellactone (CKL) 的二酯化产物,是前胡的主要活性成分,由前胡 (伞形科) 的干燥根组成。
Cas No.73069-25-7
别名(±)-白花前胡甲素
化学名(Z)-(9R,10S)-10-acetoxy-8,8-dimethyl-2-oxo-2,8,9,10-tetrahydropyrano[2,3-f]chromen-9-yl 2-methylbut-2-enoate
Canonical SMILESC/C([H])=C(C(O[C@](C1(C)C)([H])[C@](OC(C)=O)([H])C2=C(O1)C=CC(C=C3)=C2OC3=O)=O)/C
分子式C21H22O7
分子量386.40
溶解度≥ 30mg/mL in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker[1].

References:
[1]. Song YL, et al. Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquidchromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry. J Pharm Biomed Anal. 2014 Mar;90:98-110.