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1,2,3,4,6-pentagalloylglucose
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1,2,3,4,6-pentagalloylglucose图片
CAS NO:14937-32-7
包装:20mg
市场价:1407元

产品介绍
1,2,3,4,6-pentagaloylglucose (Penta-O-galloyl-β-D-glucose) 是一种从各种植物中分离出来的没食子单宁。
Cas No.14937-32-7
别名1,2,3,4,6-O-五没食子酰葡萄糖,Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose
化学名[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis[(3,4,5-trihydroxybenzoyl)oxy]oxan-2-yl]methyl 3,4,5-trihydroxybenzoate
Canonical SMILESC1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C(C(C(O2)OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5)O)O)O)OC(=O)C6=CC(=C(C(=C6)O)O)O
分子式C41H32O26
分子量940.68
溶解度≥ 50.4mg/mL in DMSO
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is a gallotannin isolated from various plants. It suppressed interleukin (IL)-4 induced signal pathway in B cell, and inhibited IgE production partially caused by increasing a population of Treg cells in conjunction with Treg-inducing factors.

References:
[1]. Viswanatha GL, et al. Alleviation of transient global ischemia/reperfusion-induced brain injury in rats with 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose isolated from Mangifera indica. Eur J Pharmacol. 2013 Nov 15;720(1-3):286-93.
[2]. Kim YH, et al. 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose increases a population of T regulatory cells and inhibits IgE production in ovalbumin-sensitized mice. Int Immunopharmacol. 2015 May;26(1):30-6.
[3]. Ahn D, et al. The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose from Curcuma longa in Caenorhabditis elegans. Biomol Ther (Seoul). 2013 Nov;21(6):442-6.