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20(S)-NotoginsenosideR2
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
20(S)-NotoginsenosideR2图片
CAS NO:80418-25-3
包装:20mg
市场价:3717元

产品介绍
20(S)-NotoginsenosideR2 是一种从三七中新分离的三七皂苷，对 6-OHDA 诱导的氧化应激和细胞凋亡具有神经保护作用。
Cas No.80418-25-3
别名三七皂苷R2,20(S)-Notoginsenoside R2; Ginsenoside Ng-R2
Canonical SMILESC/C(C)=C\CC[C@@]([C@@]([C@@]1([H])[C@@](O)([H])C[C@]2([H])[C@]3(CC[C@@](O)([H])C(C)([C@]3([H])[C@](O[C@@]4([H])[C@@](O[C@@]5([H])[C@@](O)([H])[C@](O)([H])[C@@](O)([H])CO5)([H])[C@](O)([H])[C@@](O)([H])[C@@](O4)([H])CO)([H])C[C@]26C)C)C)([H])CC[C@]16C)(O)C
分子式C41H70O13
分子量770.99
溶解度≥ 75mg/mL in EtOH
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.

References:
[1]. Meng XB, et al. P90RSK and Nrf2 Activation via MEK1/2-ERK1/2 Pathways Mediated by Notoginsenoside R2 to Prevent 6-Hydroxydopamine-Induced Apoptotic Death in SH-SY5Y Cells. Evid Based Complement Alternat Med. 2013;2013:971712.
[2]. González-Burgos E, et al. Potential neuroprotective activity of Ginseng in Parkinson's disease: a review. J Neuroimmune Pharmacol. 2015 Mar;10(1):14-29.