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ACT-373898
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ACT-373898图片
CAS NO:1433875-14-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
ACT-373898 是 Macitentan 的一种无活性羧酸代谢物。
Cas No.1433875-14-9
Canonical SMILESO=C(COC1=C(C2=CC=C(C=C2)Br)C(NS(=O)(NCCC)=O)=NC=N1)O
分子式C15H17BrN4O5S
分子量445.3
溶解度DMSO: soluble,Ethanol: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1

1.Dingemanse, J., Sidharta, P.N., Maddrey, W.C., et al.Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertensionExpert Opin. Drug Saf.13(3)391-405(2013)