| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 分子式 | C25H33N3 |
| 分子量 | 375.55 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor. AXKO-0046 has selectivity and highly potent LDHB inhibitory activity with an value EC50 of 42 nM. AXKO-0046 bounds to the potential allosteric site away from the LDHB catalytic active site. AXKO-0046 can be used to validate LDHB associated pathways in cancer metabolism[1]. [1]. Sachio Shibata, et al. Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep. 2021 Nov 1;11(1):21353. |
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