Atazanavir-d6 is the hexa- deuterated form of Atazanavir (BMS-232632), which is a highly selective HIV-1 protease inhibitor. Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. Azatanavir is a protease inhibitor (PI) approved for the treatment of HIV-1 infection. Atazanavir is a substrate and inhibitor of cytochrome P450 isozyme 3A and an inhibitor and inducer of P-glycoprotein. It has similar virologic efficacy as efavirenz and ritonavir-boosted lopinavir in antiretroviral-naive individuals.
纯度:≥98%
CAS:1092540-50-5