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Paeoniflorigenone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Paeoniflorigenone图片
CAS NO:80454-42-8
包装:1mg
市场价:7200元

产品介绍
Paeoniflorigenone是从牡丹皮中提取的一种有效成分，具有选择性诱导肿瘤细胞凋亡(apoptosis)和抗增殖作用。
Cas No.80454-42-8
别名芍药甙元酮
Canonical SMILESO=C(C1=CC=CC=C1)OC[C@H]2[C@@H]3O[C@@]4(C[C@H]2C(C[C@@]4(O3)C)=O)O
分子式C17H18O6
分子量318.32
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Paeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, induces apoptosis selectively in the cancer cell lines and exhibits antiproliferative effect[1].

Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines[1].Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells[1]. Cell Proliferation Assay[1] Cell Line: TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells

[1]. Huang Y, et al. Apoptosis-inducing activity and antiproliferative effect of Paeoniflorigenone from moutan cortex. Biosci Biotechnol Biochem. 2017;81(6):1106-1113.