| CAS NO: | 24063-71-6 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 24063-71-6 |
| 别名 | 异莪术烯醇 |
| Canonical SMILES | C=C([C@@]1([H])[C@]([C@@H](C)CC1)(O2)C/3)C[C@]2(O)C3=C(C)/C |
| 分子式 | C15H22O2 |
| 分子量 | 234.3 |
| 溶解度 | DMF: 1 mg/ml,DMSO: 1 mg/ml,Ethanol: slightly soluble |
| 储存条件 | -20°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Isocurcumenol is a sesquiterpene that has been found inC. zedoariarhizomes and has diverse biological activities.1,2,3It inhibits mycelial growth of the plant pathogenic fungusF. graminearumwhen used at a concentration of 0.5 mg/ml.1Isocurcumenol is cytotoxic to DLA, A549, KB, and K562 cancer cells (IC50s = 75.3, 75.7, 142.2, and 45.83 µg/ml, respectively).2It inhibits LPS-induced production of nitric oxide (NO) in isolated mouse peritoneal macrophages.3Isocurcumenol (50 mg/kg) reduces LPS/D-galactosamine-induced increases in serum levels of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) in a mouse model of liver injury. 1.Chen, C., Long, L., Zhang, F., et al.Antifungal activity, main active components and mechanism of Curcuma longa extract against Fusarium graminearumPLoS One13(3)e0194284(2018) 2.Lakshmi, S., Padmaja, G., and Remani, P.Antitumour effects of isocurcumenol isolated from Curcuma zedoaria rhizomes on human and murine cancer cellsInt. J. Med. Chem.253962(2011) 3.Matsuda, H., Ninomiya, K., Morikawa, T., et al.Inhibitory effect and action mechanism of sesquiterpenes from zedoariae rhizoma on D-galactosamine/lipopolysaccharide-induced liver injuryBioorg. Med. Chem. Lett.8(4)339-344(1998) |
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