您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > BAY-6035
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
BAY-6035
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BAY-6035图片
CAS NO:2247890-13-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
BAY-6035 是一种有效的、选择性的和底物竞争性的 SMYD3 抑制剂。 BAY-6035 抑制 MEKK2 肽的甲基化,IC50 为 88 nM。
Cas No.2247890-13-5
Canonical SMILESO=C(NCCC1CC1)C2=CC3=C(N(C(N4CC(C5)C5C4)=O)[C@@H](C)CC(N3)=O)C=C2
分子式C22H28N4O3
分子量396.5
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). It is 100-fold selective for SMYD3 over other histone methyltransferases. BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cells (IC50s = 88 and 70 nM, respectively). See the Structural Genomic Consortium (SGC) website for more information.

References