| CAS NO: | 17680-99-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 17680-99-8 |
| Canonical SMILES | OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC=C(C=C2)C)=O |
| 分子式 | C13H16O7 |
| 分子量 | 284.3 |
| 溶解度 | Ethanol: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | p-Cresol glucuronide is a metabolite ofp-cresol, a uremic toxin formed by bacterial fermentation of proteins in the large intestine.1It is formed fromp-cresol primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A6, but also by UGT1A9, in human liver and kidney microsomes.p-Cresol glucuronide accumulates in feces, blood, and urine of patients with chronic kidney disease (CKD).2 1.Rong, Y., and Kiang, T.K.L.Characterizations of human UDP-glucuronosyltransferase enzymes in the conjugation of p-cresolToxicol. Sci.176(2)285-296(2020) 2.Gryp, T., De Paepe, K., Vanholder, R., et al.Gut microbiota generation of protein-bound uremic toxins and related metabolites is not altered at different stages of chronic kidney diseaseKidney Int.97(6)1230-1242(2020) |
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