| Cas No. | 26246-41-3 |
| 别名 | 网状菌醇 |
| 化学名 | 6,8-dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one |
| Canonical SMILES | COC1=C(O)C=C2C(C(OC(C)=C2)=O)=C1O |
| 分子式 | C11H10O5 |
| 分子量 | 222.2 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM). It also inhibits DNA topoisomerase I when used at a concentration of 45 uM in B16F10 melanoma cells. Reticulol has antifungal activity against T. mentagrophyes with a MIC of 1.8 uM. It is cytotoxic against A427 human lung and B16F10 mouse melanoma cells at concentrations of 25 and 200 uM, respectively, and inhibits lung metastasis in mice. |
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