TC ASK 10 (Compound 10) 是一种有效的、选择性的、具有口服活性的凋亡信号调节激酶 1 (ASK1) 抑制剂，IC50 为 14 nM。 TC ASK 10 对其他代表性激酶组的抑制活性低于 50%，ASK2 除外（IC50 为 0.51 μM）。
| Cas No. | 1005775-56-3 |
| 化学名 | N-(6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl)-4-(tert-butyl)benzamide dihydrochloride |
| Canonical SMILES | CC(C)(C1=CC=C(C(NC2=CN3C=C(N4C=CN=C4)C=CC3=N2)=O)C=C1)C.Cl.Cl |
| 分子式 | C21H21N5O.2HCl |
| 分子量 | 432.35 |
| 溶解度 | <43.23mg/ml in Water;<43.23mg/ml in DMSO |
| 储存条件 | Desiccate at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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