| CAS NO: | 12656-40-5 |
| 包装: | 1mg |
| 市场价: | 7031元 |
| Cas No. | 12656-40-5 |
| Canonical SMILES | O=C(C1=CSC(/C=N/O)=N1)NC(CO)C2=N[C@@H](C(N3C(C=C(OC)C3)=O)=O)CS2 |
| 分子式 | C16H17N5O6S2 |
| 分子量 | 439.5 |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated fromS. althioticus.1It is active against Gram-positive bacteria, includingS. aureus,S. epidermidis, andS. pyogenes(MICs = 25, 25, and 3.1 µg/ml, respectively).2Althiomycin inhibits protein synthesis inE. coliwhen used at concentrations of 1 and 10 µg/ml but not in isolated rabbit reticulocytes at 100 µg/ml.3 1.Gerc, A.J., Song, L., Challis, G.L., et al.The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycinPLoS One7(9)e44673(2012) 2.Inami, K., and Shiba, T.Syntheses of althiomycin analogs in relation to antibacterial activitiesBull. Chem. Soc. Jpn.59(7)2185-2189(1986) 3.Fujimoto, H., Kinoshita, T., Suzuki, H., et al.Studies on the mode of action of althiomycinJ. Antibiot. (Tokyo)23(6)271-275(1970) |
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