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Dmt-2'fluoro-da(bz)amidite
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dmt-2'fluoro-da(bz)amidite图片
CAS NO:136834-22-5
包装:100mg
市场价:450元

产品介绍
Dmt-2'fluoro-da(bz)amidite,一种均一修饰的2'-脱氧-2'-氟代硫代磷酸酯寡核苷酸,是抗核酸酶的反义化合物,对RNA靶标具有很高的亲和力和特异性。Dmt-2'fluoro-da(bz)amidite也是5'-DMT-3'-亚磷酰胺合成的中间体。
Cas No.136834-22-5
别名N-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脱氧-2'-氟腺苷3'-[2-氰基乙基N,N-二异丙基氨基亚磷酸酯]
Canonical SMILESF[C@@H]([C@H](N1C=NC2=C1N=CN=C2NC(C3=CC=CC=C3)=O)O4)[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H]4COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7
分子式C47H51FN7O7P
分子量875.92
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5'-DMT-3'-phosphoramidite synthesis[1].

[1]. Kawasaki AM, et, al. Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J Med Chem. 1993 Apr 2;36(7):831-41.