| CAS NO: | 81-64-1 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 1g | 电议 |
Quinizarin(1,4-Dihydroxyanthraquinone)是Doxorubicin、Daunorubicin、Adriamycin等抗癌药物的一部分，通过插入方式与DNA相互作用(Kd=86.1μM)。Quinizarin是一种杀菌剂和杀虫剂，并已显示出抑制肿瘤细胞生长的能力。
| Cas No. | 81-64-1 |
| 别名 | 1,4-二羟基蒽醌; 1,4-Dihydroxyanthraquinone |
| Canonical SMILES | O=C1C2=C(C=CC=C2)C(C3=C(O)C=CC(O)=C13)=O |
| 分子式 | C14H8O4 |
| 分子量 | 240.21 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2]. 1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution[1]. [1]. VerebovA V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55. [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin. [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373. |
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