您好，欢迎来到试剂信息网！ [登录] [免费注册]
试剂信息网
发布求购
位置：首页 > 产品库 > TP0586532
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
TP0586532
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
TP0586532图片
CAS NO:2427584-96-9
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
TP0586532 是 non-hydroxamate LpxC 抑制剂 (IC50=0.101 μM)。TP0586532 作为一种低心血管风险的化合物，对肺炎克雷伯菌有效，包括耐药菌株。
Cas No.2427584-96-9
分子式C26H28N4O4
分子量460.52
溶解度DMSO : 50 mg/mL (108.57 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].

TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].

[1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.