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Lusianthridin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lusianthridin图片
CAS NO:87530-30-1
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Lusianthridin是来自Dendrobiumvenustum的天然化合物,具有抗迁移作用。Lusianthridin通过抑制Src-STAT3信号,促进c-Myc的降解。
Cas No.87530-30-1
别名4,7-二羟基-2-甲氧基-9,10-二氢菲
Canonical SMILESOC(C=C1CC2)=CC=C1C3=C2C=C(OC)C=C3O
分子式C15H14O3
分子量242.27
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling[1].

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells[1].Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively[1]. Cell Viability Assay[1] Cell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells[1].0-100 μM.

[1]. Narumol Bhummaphan, et al. Targeting of Lung Cancer Stem Cells via Src-STAT3 Suppression. Phytomedicine. 2019 Sep;62:152932.