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Surfen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Surfen图片
CAS NO:5424-37-3
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
Surfen 是一种有效的 HS(硫酸乙酰肝素)拮抗剂。
Cas No.5424-37-3
别名Aminoquincarbamide dihydrochloride
Canonical SMILESCC1=NC2=CC=C(C=C2C(N)=C1)NC(NC3=CC=C4N=C(C=C(C4=C3)N)C)=O.Cl.Cl
分子式C21H20N6O.2HCl
分子量445.35
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Heparin sulfate antagonist. Inhibits heparin sulfate-mediated cell attachment in vitro. Maintains hESCs in a pluripotent state by reversible inhibition of glycan-growth factor interactions.

Schuksz et al (2008) Surfen, a small molecule antagonist of heparan sulfate. Proc.Natl.Acad.Sci.USA 105 13074 PMID:18725627 |Huang et al (2018) Small molecule antagonist of cell surface glycosaminoglycans restricts mouse embryonic stem cells in a pluripotent state. Stem Cells. 36 45 PMID:28984039