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N-Desethylamiodarone(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Desethylamiodarone(hydrochloride)图片
CAS NO:96027-74-6
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
250mg电议

产品介绍
N-Desethylamiodarone (hydrochloride) (N-desethylamiodarone hydrochloride) 是胺碘酮的主要活性代谢物。
Cas No.96027-74-6
别名去乙基胺碘酮,N-desethylamiodarone hydrochloride; LB 33020 hydrochloride
Canonical SMILESCCNCCOc1c(I)cc(cc1I)C(=O)c1c(CCCC)oc2ccccc12Cl
分子式C23H25I2NO3•HCl
分子量653.7
溶解度DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Amiodarone is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents. It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 µM. In humans, cytochrome P450 3A is involved in the metabolism of amiodarone. N-Desethylamiodarone is the major, active metabolite of amiodarone. This compound has been used as an analytical reference standard for quantifying amiodarone in plasma samples.