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Isovaleryl-L-carnitine(chloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isovaleryl-L-carnitine(chloride)图片
CAS NO:139144-12-0
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
Isovaleryl-L-carnitine (chloride) 是 L-亮氨酸分解代谢的产物,是人中性粒细胞 Ca2+- 依赖性蛋白酶(钙蛋白酶)的有效激活剂。
Cas No.139144-12-0
别名L-异戊酰基肉碱
Canonical SMILESOC(C[C@@H](OC(CC(C)C)=O)C[N+](C)(C)C)=O.[Cl-]
分子式C12H24NO4•Cl
分子量281.8
溶解度DMF: 15 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).