CGP 52411 (DAPH) 是一种高选择性、强效、具有口服活性和 ATP 竞争性的 EGFR 抑制剂,IC50 为 0.3 μM。
Cas No. | 145915-58-8 |
别名 | DAPH |
化学名 | 5,6-bis(phenylamino)isoindoline-1,3-dione |
Canonical SMILES | O=C1NC(C(C1=C2)=CC(NC3=CC=CC=C3)=C2NC4=CC=CC=C4)=O |
分子式 | C20H15N3O2 |
分子量 | 329.35 |
溶解度 | <32.94mg/ml in DMSO;<8.23mg/ml in ethanol |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |