| CAS NO: | 2305815-72-7 |
| 包装: | 1mg |
| 市场价: | 1460元 |
| Cas No. | 2305815-72-7 |
| 化学名 | (1Z,4Z,6S,7Z,9S,10Z,12S,13Z,15S,16Z,18S,19Z,21S)-1-((S)-1-((2S,3Z,5S,6Z,8R,9Z,12Z,14S,15Z,17S,18Z,20S,21Z,23S,24Z,26S,27Z,29S,30Z,32S,33Z,35S,36Z,39Z,42Z)-44-amino-2,5-bis(4-aminobutyl)-14,17,20,23,26,29,32,35-octakis(3-guanidinopropyl)-4,7,10,13,16,19,22 |
| Canonical SMILES | CC(C[C@@](/N=C(O)/C/N=C(O)/[C@]1([H])CCCN1C([C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/C/N=C(O)/C/N=C(O)/CN)([H])CCCNC(N)=N)([H])CCCNC(N)=N)([H])C |
| 分子式 | C111H211N59O26S |
| 分子量 | 2820.31 |
| 溶解度 | Soluble to 2 mg/ml in 20% acetonitrile / Water |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1and Bad; induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. Also inhibits Pim-1-dependent growth of DU145 cellsin vitroandin vivo. Displays no effect on the growth of normal prostate epithelial RPWE-1 cells at concentrations of 10 and 20 μM. |
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