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S-Acetyl-L-glutathione
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
S-Acetyl-L-glutathione图片
CAS NO:3054-47-5
包装与价格：
包装价格(元)
5g电议
10g电议
25g电议

产品介绍
A derivative of glutathione
Cas No.3054-47-5
别名S-乙酰-L-谷胱甘肽
Canonical SMILESOC([C@@H](N)CCC(N[C@@H](CSC(C)=O)C(NCC(O)=O)=O)=O)=O
分子式C12H19N3O7S
分子量349.4
溶解度PBS (pH 7.2): 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases survival in a mouse model of HSV-1 infection.

|1. Okun, J.G., Sauer, S., B•hr, S., et al. S-Acetylglutathione normalizes intracellular glutathione content in cultured fibroblasts from patients with glutathione synthetase deficiency. J. Inherit. Metab. Dis. 27(6), 783-786 (2004).|2. Locigno, R., Pincemail, J., Henno, A., et al. S-acetyl-glutathione selectively induces apoptosis in human lymphoma cells through a GSH-independent mechanism. Int. J. Oncol. 20(1), 69-75 (2002).|3. Vogel, J.-U., Cinatl, J., Dauletbaev, N., et al. Effects of S-acetylglutathione in cell and animal model of herpes simplex virus type 1 infection. Med. Microbiol. Immunol. 194(1-2), 55-59 (2005).