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Asperfuran
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Asperfuran图片
CAS NO:129277-10-7
包装与价格:
包装价格(元)
500μg电议
2.5mg电议

产品介绍
Asperfuran 是一种由米曲霉菌株生产的抗真菌二氢苯并呋喃衍生物。
Cas No.129277-10-7
Canonical SMILESOC1=CC(O)=C2C(C[C@H](/C=C/C=C/C)O2)=C1
分子式C13H14O3
分子量218.3
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Asperfuran is a fungal metabolite originally isolated from A. oryzae that has antifungal and anticancer activities.1 It inhibits the growth of 23 fungi in a disc assay when used at a concentration of 50 μg per disc. Asperfuran inhibits chitin synthase with an IC50 value of 300 μM. It inhibits proliferation of HeLa S3 and L1210 cancer cells (IC50s = 25 μg/ml for both).

|1. Pfefferle, W., Anke, H., Bross, M., et al. Asperfuran, a novel antifungal metabolite from Aspergillus oryzae. J. Antibiot. (Tokyo) 43(6), 648-654 (1990).