α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).
| Cas No. | 148796-53-6 |
| Canonical SMILES | C/C(=C\CC\C(=C\C(O)P(=O)(O)O)\C)/CCC=C(C)C |
| 分子式 | C15H27O4P |
| 分子量 | 302.4 |
| 溶解度 | 10 mM Na2CO3: freely soluble,ETOH: >25 mg/ml,PBS pH 7.2:<25 µ g/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 µM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells. |
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