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[Met5]-Enkephalin,amide TFA
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
[Met5]-Enkephalin,amide TFA图片
包装与价格：
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
[Met5]-Enkephalin, amide TFA 是一种 δ 和 ζ 阿片受体 (opioid receptor) 激动剂。
别名5-Methionine-enkephalin amide TFA
分子式C29H37F3N6O8S
分子量686.7
溶解度Water: 100 mg/mL (145.62 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

[Met5]-Enkephalin, amide TFA is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors. δ and ζ opioid receptor[1]

[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture[1]. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine[2].

[1]. Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48. [2]. Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8.