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GRP(porcine)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
500μg电议
1mg电议

产品介绍
分子式C126H198N38O31S2•XCF3COOH
分子量2805.3
溶解度Water: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to GRP receptors on St42 human gastric cancer cells with an IC50 value of 0.35 nM. GRP increases contractility of possum (T. vulpecula) gallbladder strips with an EC50 value of 1.34 nM. In vivo, GRP increases gastrin (ED50s = 0.70 and 0.47 nmol/kg2 per hour for peak and integrated values, respectively) and pancreatic polypeptide release (ED50s = 1.2 and 1.01 nmol/kg2 per hour for peak and integrated values, respectively) in conscious cats. It also increases acid and pepsin secretion (ED50s = 1.01 and 2.06 nmol/kg2 per hour, respectively) and increases antral stomach motility in conscious cats. GRP (28 μg/kg) reduces independent ad libitum intake of sucrose and milk from bottles by rats but does not affect intraoral intake of either solution from catheters.