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Obidoxime dichloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Obidoxime dichloride图片
CAS NO:114-90-9
包装:5mg
市场价:842元

产品介绍
Obidoxime dichloride 是一种非全谱肟试剂,可作为有机磷类神经毒剂中毒的解毒剂。Obidoxime dichloride 可活化被沙林蛋白抑制的乙酰胆碱酯酶 (AChE),降低沙林蛋白的急性毒性。
Cas No.114-90-9
别名双复磷
分子式C14H16Cl2N4O3
分子量359.21
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].

Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated[1].

[1]. Kassa J,et al. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.Toxicol Mech Methods. 2015 Mar;25(3):229-33.