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5-Aminofluorescein(5-AF)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-Aminofluorescein(5-AF)图片
CAS NO:3326-34-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
500mg电议
1g电议

产品介绍
5-氨基荧光素 (5-AF) (5-AF) 是一种荧光标记物,与人血清白蛋白共价结合。
Cas No.3326-34-9
别名5-氨基荧光素; 5-AF
Canonical SMILESO=C1OC2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=C(N)C=C5
分子式C20H13NO5
分子量347.32
溶解度DMSO : ≥ 32 mg/mL (92.13 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5-Aminofluorescein (5-AF) is a new fluorescence marker, covalently bound to human serum albumin (AFL-HSA) [1]5-aminofluorescein is a pH-sensitive biomaterial, is the targeted prodrug for synthesis of FA-FITC-Arg-PTX and FA-5AF- Glu-PTX..

[1]. Ding R, et al. Pharmacokinetics of 5-aminofluorescein-albumin, a novel fluorescence marker of brain tumors during surgery. J Clin Pharmacol. 2011 May;51(5):672-8. [2]. Miao R, et al. Facile method for modification of the silicon nanowires and its application in fabrication of pH-sensitive chips. ACS Appl Mater Interfaces. 2013 Mar 13;5(5):1741-6. [3]. Wang T, et al. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein. J Am Chem Soc. 2015 Nov 4;137(43):13736-9. [4]. Shan L, et al. Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy. Int J Nanomedicine. 2015 Sep 1;10:5571-91.