5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants.
| Cas No. | 15558-50-6 |
| 别名 | 5-羟基-N-甲基色胺草酸盐 |
| Canonical SMILES | CN([H])CCC1=CNC2=CC=C(O)C=C21.OC(C(O)=O)=O |
| 分子式 | C11H14N2O•XC2H2O4 |
| 分子量 | 280.3 |
| 溶解度 | DMF: 3 mg/mL,DMSO: 3 mg/mL,PBS (pH 7.2): 2.5 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay). 5-hydroxy-Nω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-Nω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy. |
m.cnreagent.com